Patient with osteoarthritis develops hives after taking ibuprofen

DEAR DR. ROACH: I took ibuprofen for my osteoarthritis, but developed hives. Does this mean I’m allergic to all NSAIDs? What other therapeutic options do I have? -- J.B.

ANSWER: Anti-inflammatory drugs can have many allergic and allergic-type reactions, and ibuprofen is probably the most likely of all to do so.

For people with mild reactions (such as hives that go away) without swelling or shortness…